Balanitis Xerotica Obliterans(BXO) – Symptoms, Treatment, Causes



What is Balanitis Xerotica Obliterans?

Balanitis Xerotica Obliterans (BXO) also called as lichen sclerosus et atrophicus (If found in other sites besides the genitals) is a serious chronic inflammatory skin disease on the male genitalia of unknown origin.

Balanitis is characterized by the hardening of the skin tissue around the foreskin on the tip of penis. Thick white patches or a white hard ring is observed across the prepuce and prohibits its retraction.

Balanitis Xerotica Obliterans Causes

The balanitis is caused by many conditions. There are also many risk factors which predispose to balanitis

  • inflammatory condition
  • autoimmune diseases
  • diabetes
  • thyroid disease
  • vitiligo
  • infectious viral  infections
  • bacterial Infections
  • genetics is also found to be a predisposing factor in acquiring the disease.

Uncircumcised penis

Most findings also support and indicate that an uncircumcised penis is at high risk because this allows exposure to urine, warmth and moist on its skin folds and greatly contributes to the development of the disease.

Balanitis Xerotica Obliterans Symptoms

  • Itching or pruritus
  • Discomfort or burning sensation on urination
  • Reduced sensation on the tip of the penis
  • Presence of pain upon sexual arousal or erection
  • Obstruction of the urethra or passageway of urine
  • Inflamed urethra
  • Phimosis (Loss of ability retract foreskin due to constriction)
  • Paraphymosis (Skin constricted behind the glans due to inflammation)

Pathology & Problems

In the early phase of the disease, uncomfortable itch also called pruritus starts to develop. Further irritation occurs upon the passage of urine or penile discharges. The burning sensation felt in the urethra contributes to the discomfort.

  • As it progresses, Loss of sensation in the glans penis becomes more evident.
  • Pain upon urination takes place, decreasing its urinary force and stream.
  • Sexual dysfunction is present as a result of pain felt upon erection. The continued manifestations worsen as the opening of the urethra is narrowed and encircled by white lumps of hardened scar tissue.
  • Eventually, this unable the foreskin to retract (condition is know an phimosis) and the scarred tip of the penis blocks the flow of urine or semen.
  • Urinary retention takes place and causes bladder damage, forcing the waste products to backflow and inflicting harm to the kidneys. The Inflammation is worsened by infection as it starts to exacerbate the disease process if left untreated. In rare instances, reports of malignant tumors are also said to found.

Balanitis Xerotica Obliterans Diagnosis

The prevalence rate of the condition in men is highly debatable in different parts of the world, as not much has been made to study the disease in detail. Some consider it to be rare and some speculate that it is common due to the nature of the disease as it starts out asymptomatic with only mild visible changes. The evident physical formation of signs and symptoms start to occur in months to years. A diagnosis can then be achieved with thorough gathering of patient history, clinical observations, laboratory workups and cutaneous biopsy for a conclusive analysis.

Balanitis Xerotica Obliterans Treatment

  • Topical steroids
  • Tacrolimus ointments
  • Antibiotics
  • Carbon dioxide (CO2) laser surgery
  • Circumcision

At present, there is no curative therapy for balanitis xerotica obliterans (BXO). There are however numerous approaches available for palliative treatment.

1. Topical steroids

Medical practitioners often use corticosteroid creams in short courses such as, clobetasol propionate, testosterone creams for early cases relating to the involvement of the glans penis or its head. It’s effectiveness at any rate, is not a guarantee nor can reverse the damage done by the disease process as they greatly vary on its success in each individual.

2. Tacrolimus ointments

Tacrolimus ointments, a potent immunosuppressive drug is also found to be effective. Concerns about long-term use and toxicity, still outweighs its usage and to have consideration of the use of alternatives.

3. Antibiotics

Long term antimicrobial therapies are also useful to reduce the inflammation brought about by the disease. It’s observed to have softened the skin including the disappearance of pruritus and tenderness. Under any given circumstance, discontinuation on medication will positively result in relapse.


4. Carbon dioxide (CO2) laser surgery

Carbon dioxide (CO2) laser surgery is an alternative to unresponsive conservative treatment. The infrared beam of the laser is absorbed by the skin producing heat, thus vaporizing the cells within.

5. Circumcision

In adults, circumcision is also done remove the foreskin and to prevent the progression of the disease. The surgery is considered to effective but does not address the closing of the urinary meatus.

Additional surgery is required, excision of tissue and reconstructive surgery is done to correct narrowing and to create an opening. It is also advised to have regular follow up care to address any changes such as tumors.

Circumcision in children is the single most way to reduce the likelihood of developing the disease. It stops surface of the skin folds from moisture from urine, rendering it dry. This may be against some ethical cultural factors, and should be considered by its practioners. Overall, balanitis xerotica obliterans (BXO) should never be taken lightly, early detection and intervention is crucial in determining the outcome of the wellness and condition of the individual.

Picture

urethral stricture in balanitis xerotica obliterans

urethral stricture in balanitis xerotica obliterans (diagrammatic)

Image source - uronephro.com


9 Responses to “Balanitis Xerotica Obliterans(BXO) – Symptoms, Treatment, Causes”

  • john says:

    I haven’t been circumcised yet. I just read about this disease condition called balanitis xerotica obliterans and according to what I have read is that this condition is often evident in men who have not undergone circumcision. Should I be alarmed?

    • Dr. klot says:

      That is a good point. Studies shows, that when on undergoes ¬¬¬¬circumcision, he is able to decrease the chance of having this disease condition. I suggest that you undergo such as early as possible.

      • marina anderson says:

        You’re telling John to have a circumcision ASAP based on what, exactly?? He didn’t say he had BXO…you’re just another circumfetishist pushing his agenda. John should take it easy and do tons of research before undergoing any surgery. BTW circumcised men do get BXO as do women, so it is NOT exclusive to uncircumcised men.

  • kindle says:

    Last month, I went to the bathroom and noticed that I have burning sensation and had decrease urinary flow upon urination. I thought I had Urinary Tract Infection. I went to the company doctor and did some test. Afterwards he told me that I had balanitis xerotica obliterans. I was like scratching my head. I did my own research about the disease condition and underwent carbon dioxide laser treatment. Now, I am well. Thank God! I just want to share my story to give hope to those who has this kind of disease condition.

    • Draytek says:

      CO2 laser treatment is not very common for BXO and rarely mentioned by Doctors. Where did you get the treatment? Are you UK based? Thanks

  • surat says:

    I am 23 years old and married. I have been experiencing loss of sensation in my penis. And whenever my wife and I have sex, I find it hard to fully enjoy my sexual intercourse with her. I also experience having white skin patches in my penis. I told my wife that I am so scared of going to the hospital. Yet, she convinced me otherwise. The doctor told me and my wife that I have lichen sclerosus et atrophicus or the so called balanitis xerotica obliterans. I am undergoing treatment as of the moment. I just want to say to all the guys out there. Just keep strong. Having this disease won’t make you less manly. And also to tell you that you are not alone.

  • Terry Gildert says:

    I had surgery (Circumsision)14 years ago for BXO at Nottingham City Hospital. The surgery has never properly healed. I still get very regular burning sensations. Also I find myself scratching during the night, which causes bleeding and the end of my penis has slowly (over time) changed shape. I can not pee without sitting down on a toilet because the flow is so unpredictable. If I try to stand for a pee I get covered in urine. I now live in Spain. Can you advise me of what action I should take to obtain expert treatment? Thank you.

    • Anonymous says:

      My husband doctor just advised him to use a typical steroid. He is tointentionallyget an erection and let the skin split and put the steroid cream in the wound Dadaily for two months.


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